Our Pledge:
understanding, awareness, support

Our commitment to people living with rare MC4R pathway diseases extends well beyond the development of potential medicines. We embrace a responsibility to listen to the community, to help bolster both individual and collective understanding of these diseases and help transform their lives through optimal and stigma-free care.

We are committed to improving the understanding of severe obesity that results from specific MC4R pathway diseases, and we have developed resources to help share knowledge, recognize symptoms, and aid in diagnosis.

We invite people to learn more at LEAD for Rare Obesity.

And learn more about our genetic testing program Rhythm’s Uncovering Rare Obesity.

Helping to open doors to diagnosis

Genetic testing may help physicians diagnose some rare genetic diseases of obesity in individuals who may suspect there could be a specific underlying genetic cause of their obesity. However, access to genetic testing can be limited, as testing is frequently not covered by insurance.

To help expand access to testing in the United States, Rhythm launched the Uncovering Rare Obesity program. Uncovering Rare Obesity is a program sponsored by Rhythm Pharmaceuticals to help identify rare genetic diseases of obesity. Eligible individuals can receive a genetic test and two genetic counseling sessions (one before and one after the test) at no charge.

*Covers cost of test only for eligible individuals; additional restrictions apply. Click on the links below to learn more.

Information for the patient community

Information for healthcare professionals


Small company, BIG vision

Supported by a dedicated Patient Advocacy team, we are helping to turn big ideas into real change for people living with rare MC4R pathway diseases.

Our team focuses on making a meaningful difference by:

  • Acting with transparency and the highest ethical responsibility
  • Understanding and supporting the community
  • Shaping internal business practices with a focus on the patient
  • Supporting the vital work of advocacy groups, both nationally and internationally
  • Helping to raise awareness of rare genetic diseases of obesity

To reach us, please contact [email protected].